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Structural Biology Sub-Major

Biophysics (B.S.) (Major)

Effective Winter 2020

Advising

The Program in Biophysics currently offers a B.S. degree in Biophysics and a minor in Biophysics. Students interested in either option are strongly encouraged to schedule an advising appointment by contacting Student Services at biophysics@umich.edu.

Grade Policies

The Biophysics department strongly recommends that a student earn a grade of at least C– in all BIOPHYS courses and mathematics, chemistry, physics, and biology courses that are prerequisite for subsequent elections. A major program grade point average of at least 2.0 is required; this includes biophysics courses, chemistry, mathematics, physics, and biology prerequisites, and advanced electives that are part of a major plan.

Prerequisites

See specific prerequisites listed under Biological Physics Track or Structural Biology Track.

Requirements

Minimum Credits: 26

The Biophysics Major consists of two tracks:

Honors

In addition to completing all the Biophysics requirements for the major, a GPA in the major of at least 3.4 and the completion of an Honors thesis (BIOPHYS 499) with a grade of B or better, and a second Biophysics elective are required.

Approved Honors electives are all biophysics and cognate electives above, and BIOPHYS 440 or CHEM 440, CHEM 453, MCDB 422, MCDB 428, PHYSICS 402, and PHYSICS 453.Students double majoring in Biophysics and any major in the Department of Physics cannot use PHYSICS 402, 406, or 453 to satisfy the Biophysics cognate or Honors elective requirement.

Structural Biology Track (Sub-Major)

Effective Winter 2020

Prerequisites

  • MATH 115 and 116
  • CHEM 262
  • CHEM 210 / 211, 215;
  • PHYSICS 135 / 136 and 235 / 236 (or 140/141 and 240/241);
  • BIOLOGY 172 or 174 or 191 or 192 or 195.

Requirements

Minimum Credits: 26

Core:

  1. BIOPHYS / CHEM / PHYSICS 370: Physical and Chemical Principles behind Biology and Medicine
  2. BIOPHYS / MCDB 420: Structural Biology I
  3. BIOPHYS 421: Structural Biology II
  4. BIOPHYS / PHYSICS 450: Biophysics Laboratory
  5. BIOPHYS 495: Senior Seminar in Biophysics

Outside Core:

  • CHEM / BIOLCHEM 351: Fundamentals of Biochemistry or
  • MCDB 310: Introductory Biochemistry or
  • BIOLCHEM 415: Introductory Biochemistry

Electives:

One of the following:

  • BIOPHYS / CHEM / PHYSICS 417: Dynamical Processes
  • BIOPHYS / CHEM 422: Exp Methods in Structural Biology
  • BIOPHYS / PHYSICS 430: Medical Physics
  • BIOPHYS 435: Biophysical Modeling
  • BIOPHYS / CHEM 440: Biophysics of Diseases
  • BIOPHYS / CMPLXSYS / PHYSICS 445: Introduction to Information Theory for the Natural Sciences (only if taken FA20 or later)
  • BIOPHYS / CHEM 454: Biophysical Chemistry II
  • BIOPHYS / MATH / BIOINF 463: Mathematical Modeling in Biology
  • BIOPHYS / CHEM 520: Theory & Methods of Biological Chemistry
  • BIOPHYS / CHEM 521: Techniques in Biophysical Chemistry

Note: Other 400-level Physics, Chemistry, or Biology courses may be accepted, per approval of the Undergraduate Chair

Cognate:

One of the following:

  • CHEM / BIOLCHEM 451: Biochemistry I
  • MCDB 427: Molecular Biology
  • MCDB 428: Cell Biology
  • BIOLCHEM / CHEMBIO 530: Protein Protein or Protein-Ligand Interactions by NMR
  • BIOLCHEM 550: Macromolecular Structure and Function

Note: Other 400-level Physics, Chemistry, or Biology courses may be accepted, per approval of the Undergraduate Chair

Research:

At least two credits of BIOPHYS 399. Students wishing to conduct research in a laboratory outside of the Program must identify a Biophysics co-sponsor.

Honors

In addition to completing all the Biophysics requirements for the major, a GPA in the major of at least 3.4 and the completion of an Honors thesis (BIOPHYS 499) with a grade of B or better, and a second Biophysics elective are required. Approved Honors electives are all Biophysics and cognate electives above, plus CHEM 453, MCDB 422, PHYSICS 402 and PHYSICS 453.  Other courses may be accepted per approval of the Undergraduate Chair.

Structural Biology Track (Sub-Major) (Winter 2019 - Fall 2019)

Biophysics (B.S.) (Major)

Effective Winter 2020

Advising

The Program in Biophysics currently offers a B.S. degree in Biophysics and a minor in Biophysics. Students interested in either option are strongly encouraged to schedule an advising appointment by contacting Student Services at biophysics@umich.edu.

Grade Policies

The Biophysics department strongly recommends that a student earn a grade of at least C– in all BIOPHYS courses and mathematics, chemistry, physics, and biology courses that are prerequisite for subsequent elections. A major program grade point average of at least 2.0 is required; this includes biophysics courses, chemistry, mathematics, physics, and biology prerequisites, and advanced electives that are part of a major plan.

Prerequisites

See specific prerequisites listed under Biological Physics Track or Structural Biology Track.

Requirements

Minimum Credits: 26

The Biophysics Major consists of two tracks:

Honors

In addition to completing all the Biophysics requirements for the major, a GPA in the major of at least 3.4 and the completion of an Honors thesis (BIOPHYS 499) with a grade of B or better, and a second Biophysics elective are required.

Approved Honors electives are all biophysics and cognate electives above, and BIOPHYS 440 or CHEM 440, CHEM 453, MCDB 422, MCDB 428, PHYSICS 402, and PHYSICS 453.Students double majoring in Biophysics and any major in the Department of Physics cannot use PHYSICS 402, 406, or 453 to satisfy the Biophysics cognate or Honors elective requirement.

Structural Biology Track (Sub-Major)

Effective Winter 2019

Prerequisites

  • MATH 115 and 116
  • CHEM 262
  • CHEM 210 / 211, 215;
  • PHYSICS 135 / 136 and 235 / 236 (or 140/141 and 240/241);
  • BIOLOGY 171; and 172 or 174 or 195.

Requirements

Minimum Credits: 30

Core:

  1. BIOPHYS 370: Physical and Chemical Principles behind Biology and Medicine
  2. BIOPHYS 420: Structural Biology I
  3. BIOPHYS 421: Structural Biology II
  4. BIOPHYS 450: Biophysics Laboratory
  5. BIOPHYS 495: Senior Seminar in Biophysics

Outside Core:

  • CHEM 351: Fundamentals of Biochemistry or
  • MCDB 310: Introductory Biochemistry or
  • BIOLCHEM 415: Introductory Biochemistry AND
  • BIOLOGY 305: Genetics

Electives:

One of the following:

  • BIOPHYS 430: Medical Physics
  • BIOPHYS 435: Biophysical Modeling
  • BIOPHYS 440: Biophysics of Diseases
  • BIOPHYS 454: Biophysical Chemistry II
  • BIOPHYS 463: Mathematical Modeling in Biology
  • BIOPHYS 520: Theory & Methods of Biological Chemistry
  • BIOPHYS 521: Techniques in Biophysical Chemistry
  • MCDB 411: Protein Structure and Function

Note: Other 400-level Physics, Chemistry, or Biology courses may be accepted, per approval of the Undergraduate Chair

Cognate:

One of the following:

  • CHEM 451: Biochemistry I
  • MCDB 427: Molecular Biology
  • MCDB 428: Cell Biology
  • BIOLCHEM 530: Protein Protein or Protein-Ligand Interactions by NMR
  • BIOLCHEM 550: Macromolecular Structure and Function

Note: Other 400-level Physics, Chemistry, or Biology courses may be accepted, per approval of the Undergraduate Chair

Research:

At least two credits of BIOPHYS 399. Students wishing to conduct research in a laboratory outside of the Program must identify a Biophysics co-sponsor.

Distribution Policy

No course used to fulfill a major requirement may be used toward the LSA Distribution Requirement. In addition, courses in the BIOPHYS subject area may not be used toward the Distribution Requirement.

Honors

In addition to completing all the Biophysics requirements for the major, a GPA in the major of at least 3.4 and the completion of an Honors thesis (BIOPHYS 499) with a grade of B or better, and a second Biophysics elective are required. Approved Honors electives are all Biophysics and cognate electives above, and BIOPHYS 440 or CHEM 440, CHEM 453, MCDB 422, MCDB 428, PHYSICS 402 and PHYSICS 453.

Structural Biology Track (Sub-Major) (Fall 2016 - Fall 2018)

Biophysics (B.S.) (Major)

Effective Winter 2020

Advising

The Program in Biophysics currently offers a B.S. degree in Biophysics and a minor in Biophysics. Students interested in either option are strongly encouraged to schedule an advising appointment by contacting Student Services at biophysics@umich.edu.

Grade Policies

The Biophysics department strongly recommends that a student earn a grade of at least C– in all BIOPHYS courses and mathematics, chemistry, physics, and biology courses that are prerequisite for subsequent elections. A major program grade point average of at least 2.0 is required; this includes biophysics courses, chemistry, mathematics, physics, and biology prerequisites, and advanced electives that are part of a major plan.

Prerequisites

See specific prerequisites listed under Biological Physics Track or Structural Biology Track.

Requirements

Minimum Credits: 26

The Biophysics Major consists of two tracks:

Honors

In addition to completing all the Biophysics requirements for the major, a GPA in the major of at least 3.4 and the completion of an Honors thesis (BIOPHYS 499) with a grade of B or better, and a second Biophysics elective are required.

Approved Honors electives are all biophysics and cognate electives above, and BIOPHYS 440 or CHEM 440, CHEM 453, MCDB 422, MCDB 428, PHYSICS 402, and PHYSICS 453.Students double majoring in Biophysics and any major in the Department of Physics cannot use PHYSICS 402, 406, or 453 to satisfy the Biophysics cognate or Honors elective requirement.

Structural Biology Track (Sub-Major)

Effective Fall 2016

Prerequisites

  • MATH 115 and 116
  • CHEM 262
  • CHEM 210 / 211, 215;
  • PHYSICS 135 / 136 and 235 / 236 (or 140/141 and 240/241);
  • BIOLOGY 171; and 172 or 174 or 195.

Requirements

Minimum Credits: 30

Core:

  1. BIOPHYS 370: Physical and Chemical Principles behind Biology and Medicine
  2. BIOPHYS 420: Structural Biology I
  3. BIOPHYS 421: Structural Biology II
  4. BIOPHYS 450: Biophysics Laboratory
  5. BIOPHYS 495: Senior Seminar in Biophysics

Outside Core:

  • CHEM 351: Fundamentals of Biochemistry or
  • MCDB 310: Introductory Biochemistry or
  • BIOLCHEM 415: Introductory Biochemistry AND
  • BIOLOGY 305: Genetics

Electives:

One of the following:

  • BIOPHYS 430: Medical Physics
  • BIOPHYS 435: Biophysical Modeling
  • BIOPHYS 440: Biophysics of Diseases
  • BIOPHYS 454: Biophysical Chemistry II
  • BIOPHYS 463: Mathematical Modeling in Biology
  • BIOPHYS 520: Theory & Methods of Biological Chemistry
  • BIOPHYS 521: Techniques in Biophysical Chemistry
  • MCDB 411: Protein Structure and Function

Note: Other 400-level Physics, Chemistry, or Biology courses may be accepted, per approval of the Undergraduate Chair

Cognate:

One of the following:

  • CHEM 451: Biochemistry I
  • MCDB 427: Molecular Biology
  • MCDB 428: Cell Biology
  • BIOLCHEM 530: Protein Protein or Protein-Ligand Interactions by NMR
  • BIOLCHEM 550: Macromolecular Structure and Function

Note: Other 400-level Physics, Chemistry, or Biology courses may be accepted, per approval of the Undergraduate Chair

Students double majoring in Biophysics and any major in the Department of Physics cannot use PHYSICS 402, 406, or 453 to satisfy the Biophysics cognate or Honors elective requirement.

Research:

At least two credits of BIOPHYS 399. Students wishing to conduct research in a laboratory outside of the Program must identify a Biophysics co-sponsor.

Distribution Policy

No course used to fulfill a major requirement may be used toward the LSA Distribution Requirement. In addition, courses in the BIOPHYS subject area may not be used toward the Distribution Requirement.

Honors

In addition to completing all the Biophysics requirements for the major, a GPA in the major of at least 3.4 and the completion of an Honors thesis (BIOPHYS 499) with a grade of B or better, and a second Biophysics elective are required. Approved Honors electives are all Biophysics and cognate electives above, and BIOPHYS 440 or CHEM 440, CHEM 453, MCDB 422, MCDB 428, PHYSICS 402 and PHYSICS 453.