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Biochemistry Major

Effective Winter 2024

Exclusions:

Students who elect a major in Biochemistry may not elect the following majors: Biomolecular Science, Chemistry, Interdisciplinary Chemical Sciences, Biology; General Biology; Molecular, Cellular, and Developmental Biology (formerly known as Cell and Molecular Biology, or CMB); Cellular and Molecular Biomedical Science Major (formerly known as Cellular and Molecular Biology and Biomedical Engineering, or CMB:BME); Ecology and Evolutionary Biology; Microbiology; or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

Advising

Students develop a plan for the major in consultation with a program advisor. Those interested in a B.S. degree with a major in Chemistry, Biochemistry, Biomolecular Science, or Interdisciplinary Chemical Sciences are urged to consult a program advisor during their first or sophomore years. Prospective majors are advised that further study in chemistry requires adequate performance in early chemistry courses (preferably B- or better) as well as in the mathematics and physics prerequisites. Students interested in an Honors degree should see the Chemistry Honors advisor. Appointments are scheduled online at http://lsa.umich.edu/chem/undergraduates/advising.html. Students interested in the joint program with the College of Engineering should make an appointment with Newnan Academic Advising Center and then make an appointment to see a Chemistry Department advisor online.

Grade Policies

The department strongly recommends that a student earn a grade of at least C– in all CHEM courses and mathematics, physics, and biology courses which are prerequisites for subsequent elections. A major program grade point average of at least 2.0 is required; this includes chemistry courses, mathematics and physics prerequisites and advanced electives which are part of a plan for the major. Prerequisites must be taken for a grade. Students must request any change in a grade before the end of the next regular academic term.

 

Prerequisites

    • BIOLOGY 171 and either 172 or 174; or BIOLOGY 192; or BIOLOGY 195
    • CHEM 210/211 and CHEM 215
    • MATH 115 (or 120) and MATH 116 (or 121)
    • MATH 215 or CHEM 262
    • PHYSICS [125/127 or 135/136 or 139 or 140/141 or 150/151 or 160/161] and PHYSICS [126/128 or 235/236 or 239 or 240/241 or 250/251 or 260/261].

 

Requirements

Minimum Credits: 37

Must include:

  1. Core: BIOLOGY 305; CHEM 260 or CHEM 230 & 261, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352 or 353, 451, 452, 453.
    *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM / BIOPHYS / PHYSICS 417: Dynamic Biophysics (3)
    • CHEM 419: Intermediate Physical Organic Chemistry(3)
    • CHEM 420: Advanced Organic Chemistry (3)
    • CHEM 421: Organic Chemistry of Drug Design (3)
    • CHEM / BIOPHYS 440: Biophysics of Disease (3)
    • CHEM 447: Physical Methods of Analysis (3)
    • CHEM 455: Special Topics in Biochemistry (3)
    • CHEM 461: Physical Chemistry I (3)
    • CHEM 474: Environmental Chemistry (3)
    • CHEM / BIOPHYS 521: Biophysical Chemistry II (3)
    • BIOPHYS 417/CHEM 417/PHYSICS 417: Dynamical Processes in Biophysics (3)
    • BIOPHYS 420: Structural Biology I (3) (only if taken W17 or later)
    • BIOPHYS 421: Structural Biology: Biophysical Controversies (3)
    • BIOPHYS / PHYSICS 430: Medical Physics (3) (only if taken WN20 or later)
    • BIOPHYS 435: Biophysical Modeling (3)
    • BIOPHYS / CHEM 440: Biophysics of Disease (3)
    • BIOPHYS / CHEM 520: Methods of Biophysical Chemistry (3)
    • BIOPHYS / CHEM 521: Biophysical Chemistry II (3)
    • MCDB 408: Genomic Biology (3)
    • MCDB 411: Protein Biochemistry) (3)
    • MCDB 417: Chromosome Structure and Function (3)
    • MCDB 420: Structural Biology: The Architecture of Life (3)
    • MCDB 422: Brain Development, Plasticity, and Circuits (3) (only if taken W17 or later)
    • MCDB 427: Molecular Biology (3)
    • MCDB 428: Cell Biology (3)
    • MCDB 430: Molecular Biology of Plants (3)
    • MCDB 431: Plant Biochemistry (3)
    • MCDB 434: Protein Misfolding Diseases (3)
    • MCDB 435: Intracellular Trafficking (3)
    • MCDB 436: Introductory Immunology (3)
    • MCDB 440: Cell Cycle Control and Cancer (3)
    • MCDB 441: Cell Biology of Disease (3)
    • MCDB 448: Telomerase Function in Stem Cells and Cancers (3)
    • MCDB 472:Building a Synthetic Cell (3)
    • MICRBIOL 405: Medical Microbiology and Infectious Diseases (3)
    • PHRMACOL 310: Pharmacology and Therapeutics (3)
    • PHRMACOL 425: Development of New Medications: Pharmacology in Action (3)
    • PHYSIOL 502: Human Physiology (4)

  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are BIOPHYS 450, MCDB 429, CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Distribution Policy

No course used to fulfill a major requirement may be used toward the LSA Distribution Requirement. In addition, courses in the CHEM subject area may not be used toward the Distribution Requirement.

Honors

Qualified students may elect an Honors major. The Honors major requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

Teaching Certificate

Those seeking a B.S. with a teaching certificate in Chemistry must fulfill departmental as well as School of Education requirements. Students who plan to earn a teaching certificate with a teaching major or minor in Chemistry should contact the School of Education Teacher Education Office.

Biochemistry [B.S.] (Major) (Winter 2023 - Fall 2023)

Effective Winter 2023

Exclusions:

Students who elect a major in Biochemistry may not elect the following majors: Biology; General Biology; Molecular, Cellular, and Developmental Biology (formerly known as Cell and Molecular Biology, or CMB); Cellular and Molecular Biomedical Science Major (formerly known as Cellular and Molecular Biology and Biomedical Engineering, or CMB:BME); Ecology and Evolutionary Biology; Microbiology; or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

Advising

Students develop a plan for the major in consultation with a program advisor. Those interested in a B.S. degree with a major in Chemical Science (120 credits) or the specialized program leading to the Bachelor of Science in Chemistry (124 credits) are urged to consult a program advisor during the freshman and/or sophomore years. Prospective majors are advised that further study in chemistry requires adequate performance in early chemistry courses (preferably B- or better) as well as in the mathematics and physics prerequisites. Students interested in an Honors degree should see the Chemistry Honors advisor. Appointments are scheduled online at http://lsa.umich.edu/chem/undergraduates/advising.html. Students interested in the joint program with the College of Engineering should make an appointment with the Newnan Engineering/LSA Joint Program Advisor [Academic Advising Center, 1255 Angell Hall, 734.764.0332] and then make an appointment to see a Chemistry Department advisor online.

Grade Policies

The department strongly recommends that a student earn a grade of at least C– in all CHEM courses and mathematics, physics, and biology courses which are prerequisites for subsequent elections. A major program grade point average of at least 2.0 is required; this includes chemistry courses, mathematics and physics prerequisites and advanced electives which are part of a plan for the major. Prerequisites must be taken for a grade. Students must request any change in a grade before the end of the next regular academic term.

 

Prerequisites

    • BIOLOGY 171 and either 172 or 174; or BIOLOGY 192; or BIOLOGY 195
    • CHEM 210/211 and CHEM 215
    • MATH 115 (or 120) and MATH 116 (or 121)
    • MATH 215 or CHEM 262
    • PHYSICS [125/127 or 135/136 or 139 or 140/141 or 150/151 or 160/161] and PHYSICS [126/128 or 235/236 or 239 or 240/241 or 250/251 or 260/261].

 

Requirements

Minimum Credits: 37

Must include:

  1. Core: BIOLOGY 305; CHEM 260 or CHEM 230 & 261, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352 or 353, 451, 452, 453.
    *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM / BIOPHYS / PHYSICS 417: Dynamic Biophysics (3)
    • CHEM 419: Intermediate Physical Organic Chemistry(3)
    • CHEM 420: Advanced Organic Chemistry (3)
    • CHEM 421: Organic Chemistry of Drug Design (3)
    • CHEM / BIOPHYS 440: Biophysics of Disease (3)
    • CHEM 447: Physical Methods of Analysis (3)
    • CHEM 455: Special Topics in Biochemistry (3)
    • CHEM 461: Physical Chemistry I (3)
    • CHEM 474: Environmental Chemistry (3)
    • CHEM / BIOPHYS 521: Biophysical Chemistry II (3)
    • BIOPHYS 417/CHEM 417/PHYSICS 417: Dynamical Processes in Biophysics (3)
    • BIOPHYS 420: Structural Biology I (3) (only if taken W17 or later)
    • BIOPHYS / PHYSICS 430: Medical Physics (3) (only if taken WN20 or later)
    • BIOPHYS 435: Biophysical Modeling (3)
    • BIOPHYS / CHEM 440: Biophysics of Disease (3)
    • BIOPHYS / CHEM 520: Methods of Biophysical Chemistry (3)
    • BIOPHYS / CHEM 521: Biophysical Chemistry II (3)
    • MCDB 408: Genomic Biology (3)
    • MCDB 411: Protein Biochemistry) (3)
    • MCDB 417: Chromosome Structure and Function (3)
    • MCDB 420: Structural Biology: The Architecture of Life (3)
    • MCDB 422: Brain Development, Plasticity, and Circuits (3) (only if taken W17 or later)
    • MCDB 427: Molecular Biology (3)
    • MCDB 428: Cell Biology (3)
    • MCDB 430: Molecular Biology of Plants (3)
    • MCDB 431: Plant Biochemistry (3)
    • MCDB 434: Protein Misfolding Diseases (3)
    • MCDB 435: Intracellular Trafficking (3)
    • MCDB 436: Introductory Immunology (3)
    • MCDB 440: Cell Cycle Control and Cancer (3)
    • MCDB 441: Cell Biology of Disease (3)
    • MCDB 448: Telomerase Function in Stem Cells and Cancers (3)
    • MCDB 472:Building a Synthetic Cell (3)
    • MICRBIOL 405: Medical Microbiology and Infectious Diseases (3)
    • PHRMACOL 310: Pharmacology and Therapeutics (3)
    • PHRMACOL 425: Development of New Medications: Pharmacology in Action (3)
    • PHYSIOL 502: Human Physiology (3)

  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are BIOPHYS 450, MCDB 429, CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Distribution Policy

No course used to fulfill a major requirement may be used toward the LSA Distribution Requirement. In addition, courses in the CHEM subject area may not be used toward the Distribution Requirement.

Honors

Qualified students may elect an Honors major. The Honors major requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

Teaching Certificate

Those seeking a B.S. or B.S. Chem. Degree with a teaching certificate in Chemistry must fulfill departmental as well as School of Education requirements. Students who plan to earn a teaching certificate with a teaching major or minor in Chemistry should contact the School of Education Teacher Education Office.

Biochemistry [B.S.] (Major) (Winter 2020 - Fall 2022)

Effective Winter 2020

Exclusions:

Students who elect a major in Biochemistry may not elect the following majors: Biology; General Biology; Molecular, Cellular, and Developmental Biology (formerly known as Cell and Molecular Biology, or CMB); Cellular and Molecular Biomedical Science Major (formerly known as Cellular and Molecular Biology and Biomedical Engineering, or CMB:BME); Ecology and Evolutionary Biology; Microbiology; or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

Advising

Students develop a plan for the major in consultation with a program advisor. Those interested in a B.S. degree with a major in Chemical Science (120 credits) or the specialized program leading to the Bachelor of Science in Chemistry (124 credits) are urged to consult a program advisor during the freshman and/or sophomore years. Prospective majors are advised that further study in chemistry requires adequate performance in early chemistry courses (preferably B- or better) as well as in the mathematics and physics prerequisites. Students interested in an Honors degree should see the Chemistry Honors advisor. Appointments are scheduled online at http://lsa.umich.edu/chem/undergraduates/advising.html. Students interested in the joint program with the College of Engineering should make an appointment with John Stratman [Academic Advising Center, 1255 Angell Hall, 734.764.0332] and then make an appointment to see a chemistry department advisor online.

Grade Policies

The department strongly recommends that a student earn a grade of at least C– in all CHEM courses and mathematics, physics, and biology courses which are prerequisites for subsequent elections. A major program grade point average of at least 2.0 is required; this includes chemistry courses, mathematics and physics prerequisites and advanced electives which are part of a plan for the major. Prerequisites must be taken for a grade. Students must request any change in a grade before the end of the next regular academic term.

 

Prerequisites

    • BIOLOGY 171 and either 172 or 174; or BIOLOGY 192; or BIOLOGY 195
    • CHEM 210/211 and CHEM 215
    • MATH 115 (or 120) and MATH 116 (or 121)
    • MATH 215 or CHEM 262
    • PHYSICS [125/127 or 135/136 or 139 or 140/141 or 160/161] and PHYSICS [126/128 or 235/236 or 239 or 240/241 or 260/261].

 

Requirements

Minimum Credits: 37

Must include:

  1. Core: BIOLOGY 305; CHEM 260, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352, 451, 452, 453.
    *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM / BIOPHYS / PHYSICS 417: Dynamic Biophysics (3)
    • CHEM 420: Advanced Organic Chemistry (3)
    • CHEM / BIOPHYS 440: Biophysics of Disease (3)
    • CHEM 447: Physical Methods of Analysis (3)
    • CHEM 454: Biophysical Chem II: Macromolecular Structure, Dynamics (3)
    • CHEM 455: Special Topics in Biochemistry (3)
    • CHEM 461: Physical Chemistry I (3)
    • CHEM / AOSS 467 / EARTH 465 / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • CHEM / BIOPHYS 521: Biophysical Chemistry II (3)
    • CHEM / BIOLCHEM / MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • CHEM / BIOLCHEM 673: Enzyme Kinetics (2)
    • AOSS / CHEM 467 / EARTH 465 / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • BIOLCHEM / CHEM / MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • BIOLCHEM / CHEMBIO 530: Structural Biology (3)
    • BIOLCHEM 541: Molecular Genetics (3)
    • BIOLCHEM 550: Macromolecular Structure and Function (3)
    • BIOLCHEM / PHYSIOL / PHRMACOL 576: Signal transduction (1)
    • BIOLCHEM 640: Post-transcriptional Gene Regulation (2)
    • BIOLCHEM 650: Mechanisms of Eukaryotic Gene Expression (3)
    • BIOLCHEM / CHEM 673: Enzyme Kinetics (2)
    • BIOLCHEM / CDB / MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • BIOPHYS 417/CHEM 417/PHYSICS 417: Dynamical Processes in Biophysics (3)
    • BIOPHYS 420: Structural Biology I (3) (only if taken W17 or later)
    • BIOPHYS / PHYSICS 430: Medical Physics (3) (only if taken WN20 or later)
    • BIOPHYS 435: Biophysical Modeling (3)
    • BIOPHYS / CHEM 440: Biophysics of Disease (3)
    • BIOPHYS / CHEM 521: Biophysical Chemistry II (3)
    • CDB / BIOLCHEM / MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • CHEMBIO / BIOLCHEM 530: Structural Biology (3)
    • EARTH 465 / CHEM / AOSS / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • ENSCEN / CHEM / AOSS 367 / EARTH / ENVIRON 467: Biogeochemical Cycles (3)
    • ENVIRON / CHEM / AOSS 467 /EARTH 465 / ENSCEN 467: Biogeochemical Cycles (3)
    • MCDB 405: Molecular Basis of Development (3)
    • MCDB 411: Protein Biochemistry) (3)
    • MCDB 417: Chromosome Structure and Function (3)
    • MCDB 418: Endocrinology (3)
    • MCDB 422: Brain Development, Plasticity, and Circuits (3) (only if taken W17 or later)
    • MCDB 427: Molecular Biology (3)
    • MCDB 428: Cell Biology (3)
    • MCDB 431: Plant Biochemistry (3)
    • MCDB 435: Intracellular Trafficking (3)
    • MCDB 436: Introductory Immunology (3)
    • MCDB 437: Microbial Communities & Development (3)
    • MCDB 441: Cell Biology of Disease (3)
    • MCDB 471: Advanced Methods in Biochemistry (3)
    • MEDCHEM / BIOLCHEM / CHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • MICRBIOL / BIOLCHEM / CDB 675: Advanced Topics in Protein Trafficking and Localization (2)
    • PHRMACOL 576/BIOLCHEM 576/PHYSIOL 576: Signal transduction (1)
    • PHYSICS / CHEM / BIOPHYS 417: Dynamic Biophysics (3)
    • PHYSICS / BIOPHYS 430: Medical Physics (3) (only if taken WN20 or later)
    • PHYSIOL / BIOLCHEM / PHRMACOL 576: Signal transduction (1)
  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are MCDB 429, CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Distribution Policy

No course used to fulfill a major requirement may be used toward the LSA Distribution Requirement. In addition, courses in the CHEM subject area may not be used toward the Distribution Requirement.

Honors

Qualified students may elect an Honors major. The Honors major requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

Teaching Certificate

Those seeking a B.S. or B.S. Chem. Degree with a teaching certificate in Chemistry must fulfill departmental as well as School of Education requirements. Students who plan to earn a teaching certificate with a teaching major or minor in Chemistry should contact the School of Education Teacher Education Office.

Biochemistry [B.S.] (Major) (Fall 2018 - Fall 2019)

Effective Fall 2018

Exclusions:

Students who elect a major in Biochemistry may not elect the following majors: Biology; General Biology; Molecular, Cellular, and Developmental Biology (formerly known as Cell and Molecular Biology, or CMB); Cellular and Molecular Biomedical Science Major (formerly known as Cellular and Molecular Biology and Biomedical Engineering, or CMB:BME); Ecology and Evolutionary Biology; Microbiology; or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

Advising

Students develop a plan for the major in consultation with a program advisor. Those interested in a B.S. degree with a major in Chemical Science (120 credits) or the specialized program leading to the Bachelor of Science in Chemistry (124 credits) are urged to consult a program advisor during the freshman and/or sophomore years. Prospective majors are advised that further study in chemistry requires adequate performance in early chemistry courses (preferably B- or better) as well as in the mathematics and physics prerequisites. Students interested in an Honors degree should see the Chemistry Honors advisor. Appointments are scheduled online at http://lsa.umich.edu/chem/undergraduates/advising.html. Students interested in the joint program with the College of Engineering should make an appointment with John Stratman [Academic Advising Center, 1255 Angell Hall, 734.764.0332] and then make an appointment to see a chemistry department advisor online.

Grade Policies

The department strongly recommends that a student earn a grade of at least C– in all CHEM courses and mathematics, physics, and biology courses which are prerequisites for subsequent elections. A major program grade point average of at least 2.0 is required; this includes chemistry courses, mathematics and physics prerequisites and advanced electives which are part of a plan for the major. Prerequisites must be taken for a grade. Students must request any change in a grade before the end of the next regular academic term.

 

Prerequisites

    • BIOLOGY 171 and either 172 or 174; or BIOLOGY 192; or BIOLOGY 195
    • CHEM 210/211 and CHEM 215
    • MATH 115 (or 120) and MATH 116 (or 121)
    • MATH 215 or CHEM 262
    • PHYSICS [125/127 or 135/136 or 139 or 140/141 or 160/161] and PHYSICS [126/128 or 235/236 or 239 or 240/241 or 260/261].

 In cases where a student is transferring to Biochemistry from outside the University or is entering later, from another major, the student may be awarded an override for Genetics after completion of only one of either BIOLOGY 171 or 172 where taking the other would be a burden for timely graduation. The override request must come from a Biochemistry department advisor along with the assurance that the student has been informed of the material from BIOLOGY 171 or 172 that he or she needs to review prior to enrolling in the Genetics course.

Requirements

Minimum Credits: 37

Must include:

  1. Core: BIOLOGY 305; CHEM 260, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352, 451, 452, 453.
    *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM / BIOPHYS / PHYSICS 417: Dynamic Biophysics (3)
    • CHEM 420: Advanced Organic Chemistry (3)
    • CHEM / BIOPHYS 440: Biophysics of Disease (3)
    • CHEM 447: Physical Methods of Analysis (3)
    • CHEM 454: Biophysical Chem II: Macromolecular Structure, Dynamics (3)
    • CHEM 455: Special Topics in Biochemistry (3)
    • CHEM 461: Physical Chemistry I (3)
    • CHEM / AOSS 467 / EARTH 465 / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • CHEM / BIOPHYS 521: Biophysical Chemistry II (3)
    • CHEM / BIOLCHEM / MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • CHEM / BIOLCHEM 673: Enzyme Kinetics (2)
    • AOSS / CHEM 467 / EARTH 465 / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • BIOLCHEM / CHEM / MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • BIOLCHEM / CHEMBIO 530: Structural Biology (3)
    • BIOLCHEM 541: Molecular Genetics (3)
    • BIOLCHEM 550: Macromolecular Structure and Function (3)
    • BIOLCHEM / PHYSIOL / PHRMACOL 576: Signal transduction (1)
    • BIOLCHEM 640: Post-transcriptional Gene Regulation (2)
    • BIOLCHEM 650: Mechanisms of Eukaryotic Gene Expression (3)
    • BIOLCHEM / CHEM 673: Enzyme Kinetics (2)
    • BIOLCHEM / CDB / MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • BIOPHYS / CHEM / PHYSICS 417: Dynamical Processes in Biophysics (3)
    • BIOPHYS 420: Structural Biology I (3) (only if taken W17 or later)
    • BIOPHYS / PHYSICS 430: Medical Physics (3) (only if taken WN20 or later)
    • BIOPHYS 435: Biophysical Modeling (3)
    • BIOPHYS / CHEM 440: Biophysics of Disease (3)
    • BIOPHYS / CHEM 521: Biophysical Chemistry II (3)
    • CDB / BIOLCHEM / MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • CHEMBIO / BIOLCHEM 530: Structural Biology (3)
    • EARTH 465 / CHEM / AOSS / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • ENSCEN / CHEM / AOSS 467 / EARTH 465 / ENVIRON 467: Biogeochemical Cycles (3)
    • ENVIRON / CHEM / AOSS 467 / EARTH 465 / ENSCEN 467: Biogeochemical Cycles (3)
    • MCDB 405: Molecular Basis of Development (3)
    • MCDB 411: Protein Biochemistry) (3)
    • MCDB 417: Chromosome Structure and Function (3)
    • MCDB 418: Endocrinology (3)
    • MCDB 422: Brain Development, Plasticity, and Circuits (3) (only if taken W17 or later)
    • MCDB 427: Molecular Biology (3)
    • MCDB 428: Cell Biology (3)
    • MCDB 431: Plant Biochemistry (3)
    • MCDB 435: Intracellular Trafficking (3)
    • MCDB 436: Introductory Immunology (3)
    • MCDB 437: Microbial Communities & Development (3)
    • MCDB 441: Cell Biology of Disease (3)
    • MCDB 471: Advanced Methods in Biochemistry (3)
    • MEDCHEM / BIOLCHEM / CHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • MICRBIOL / BIOLCHEM / CDB 675: Advanced Topics in Protein Trafficking and Localization (2)
    • PHRMACOL / BIOLCHEM / PHYSIOL 576: Signal transduction (1)
    • PHYSICS / CHEM / BIOPHYS 417: Dynamic Biophysics (3)
    • PHYSIOL / BIOLCHEM / PHRMACOL 576: Signal transduction (1)
  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are MCDB 429, CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Distribution Policy

No course used to fulfill a major requirement may be used toward the LSA Distribution Requirement. In addition, courses in the CHEM and BIOLCHEM

Honors

Qualified students may elect an Honors major. The Honors major requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

Teaching Certificate

Those seeking a B.S. or B.S. Chem. Degree with a teaching certificate in Chemistry must fulfill departmental as well as School of Education requirements. Students who plan to earn a teaching certificate with a teaching major or minor in Chemistry should contact the School of Education Teacher Education Office.

Biochemistry [B.S.] (Major) (Fall 2015 - Summer 2018)

Effective Fall 2015

Exclusions:

Students who elect a major in Biochemistry may not elect the following majors: Biology, General Biology, Cell and Molecular Biology, CMB:Biomedical Engineering, Ecology and Evolutionary Biology, Microbiology, or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

Advising

Students develop a plan for the major in consultation with a program advisor. Those interested in a B.S. degree with a major in Chemical Science (120 credits) or the specialized program leading to the Bachelor of Science in Chemistry (124 credits) are urged to consult a program advisor during the freshman and/or sophomore years. Prospective majors are advised that further study in chemistry requires adequate performance in early chemistry courses (preferably B- or better) as well as in the mathematics and physics prerequisites. Students interested in an Honors degree should see the Chemistry Honors advisor. Appointments are scheduled online at http://lsa.umich.edu/chem/undergraduates/advising.html. Students interested in the joint program with the College of Engineering should make an appointment with John Stratman [Academic Advising Center, 1255 Angell Hall, 734.764.0332] and then make an appointment to see a chemistry department advisor online.

Grade Policies

The department strongly recommends that a student earn a grade of at least C– in all CHEM courses and mathematics, physics, and biology courses which are prerequisites for subsequent elections. A major program grade point average of at least 2.0 is required; this includes chemistry courses, mathematics and physics prerequisites and advanced electives which are part of a plan for the major. Prerequisites must be taken for a grade. Students must request any change in a grade before the end of the next regular academic term.

 

Prerequisites

    • BIOLOGY 171 and 172
    • CHEM 210/211, 215
    • MATH 115 (or 120), 116 (or 121), 215 (or the equivalent)
    • PHYSICS [135/136 or 140/141] and [235/236 or 240/241].

 In cases where a student is transferring to Biochemistry from outside the University or is entering later, from another major, the student may be awarded an override for Genetics after completion of only one of either BIOLOGY 171 or 172 where taking the other would be a burden for timely graduation. The override request must come from a Biochemistry department advisor along with the assurance that the student has been informed of the material from BIOLOGY 171 or 172 that he or she needs to review prior to enrolling in the Genetics course.

Requirements

Must include:

  1. Core: BIOLOGY 305; CHEM 260, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352, 451, 452, 453.
    *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM 417/BIOPHYS 417/PHYSICS 417: Dynamic Biophysics (3)
    • CHEM 420: Advanced Organic Chemistry (3)
    • CHEM 440/BIOPHYS 440: Biophysics of Disease (3)
    • CHEM 447: Physical Methods of Analysis (3)
    • CHEM 454: Biophysical Chem II: Macromolecular Structure, Dynamics (3)
    • CHEM 455: Special Topics in Biochemistry (3)
    • CHEM 461: Physical Chemistry I (3)
    • CHEM 467/AOSS 467/EARTH 465/ENSCEN 467/ENVIRON 467: Biogeochemical Cycles (3)
    • CHEM 521/BIOPHYS 521: Biophysical Chemistry II (3)
    • CHEM 528/BIOLCHEM 528/MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • CHEM 673/BIOLCHEM 673: Enzyme Kinetics (2)
    • AOSS 467/CHEM 467/EARTH 465/ENSCEN 467/ENVIRON 467: Biogeochemical Cycles (3)
    • BIOLCHEM 528/CHEM 528/MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • BIOLCHEM 530/CHEMBIO 530: Structural Biology (3)
    • BIOLCHEM 541: Molecular Genetics (3)
    • BIOLCHEM 550: Macromolecular Structure and Function (3)
    • BIOLCHEM 576/PHYSIOL 576/PHRMACOL 576: Signal transduction (1)
    • BIOLCHEM 640: Post-transcriptional Gene Regulation (2)
    • BIOLCHEM 650: Mechanisms of Eukaryotic Gene Expression (3)
    • BIOLCHEM 673/CHEM 673: Enzyme Kinetics (2)
    • BIOLCHEM 675/CDB 675/MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • BIOPHYS 417/CHEM 417/PHYSICS 417: Dynamical Processes in Biophysics (3)
    • BIOPHYS 420: Structural Biology I (3) (W17)
    • BIOPHYS 435: Biophysical Modeling (3)
    • BIOPHYS 440/CHEM 440: Biophysics of Disease (3)
    • BIOPHYS 521/CHEM 521: Biophysical Chemistry II (3)
    • CDB 675/BIOLCHEM 675/MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • CHEMBIO 530/BIOLCHEM 530: Structural Biology (3)
    • EARTH 465/CHEM 467/AOSS 467/ ENSCEN 467/ENVIRON 467: Biogeochemical Cycles (3)
    • ENSCEN 467/CHEM 467/AOSS 467/EARTH 465/ENVIRON 467: Biogeochemical Cycles (3)
    • ENVIRON 467/CHEM 467/AOSS 467/EARTH 465/ENSCEN 467: Biogeochemical Cycles (3)
    • MCDB 405: Molecular Basis of Development (3)
    • MCDB 411: Protein Biochemistry) (3)
    • MCDB 417: Chromosome Structure and Function (3)
    • MCDB 418: Endocrinology (3)
    • MCDB 422: Brain Development, Plasticity, and Circuits (3) (W17)
    • MCDB 427: Molecular Biology (3)
    • MCDB 428: Cell Biology (3)
    • MCDB 431: Plant Biochemistry (3)
    • MCDB 435: Intracellular Trafficking (3)
    • MCDB 436: Introductory Immunology (3)
    • MCDB 437: Microbial Communities & Development (3)
    • MCDB 441: Cell Biology of Disease (3)
    • MCDB 471: Advanced Methods in Biochemistry (3)
    • MEDCHEM 528/BIOLCHEM 528/CHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • MICRBIOL 675/BIOLCHEM 675/CDB 675: Advanced Topics in Protein Trafficking and Localization (2)
    • PHRMACOL 576/BIOLCHEM 576/PHYSIOL 576: Signal transduction (1)
    • PHYSICS 417CHEM 417/BIOPHYS 417: Dynamic Biophysics (3)
    • PHYSIOL 576/BIOLCHEM 576/PHRMACOL 576: Signal transduction (1)
  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are MCDB 429, CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Distribution Policy

No course used to fulfill a major requirement may be used toward the LSA Distribution Requirement. In addition, courses in the CHEM and BIOLCHEM

Honors

Qualified students may elect an Honors major. The Honors major requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

Teaching Certificate

Those seeking a B.S. or B.S. Chem. Degree with a teaching certificate in Chemistry must fulfill departmental as well as School of Education requirements. Students who plan to earn a teaching certificate with a teaching major or minor in Chemistry should contact the School of Education Teacher Education Office.