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Biochemistry Major

Effective Winter 2020

Exclusions:

Students who elect a major in Biochemistry may not elect the following majors: Biology; General Biology; Molecular, Cellular, and Developmental Biology (formerly known as Cell and Molecular Biology, or CMB); Cellular and Molecular Biomedical Science Major (formerly known as Cellular and Molecular Biology and Biomedical Engineering, or CMB:BME); Ecology and Evolutionary Biology; Microbiology; or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

Advising

Students develop a plan for the major in consultation with a program advisor. Those interested in a B.S. degree with a major in Chemical Science (120 credits) or the specialized program leading to the Bachelor of Science in Chemistry (124 credits) are urged to consult a program advisor during the freshman and/or sophomore years. Prospective majors are advised that further study in chemistry requires adequate performance in early chemistry courses (preferably B- or better) as well as in the mathematics and physics prerequisites. Students interested in an Honors degree should see the Chemistry Honors advisor. Appointments are scheduled online at http://lsa.umich.edu/chem/undergraduates/advising.html. Students interested in the joint program with the College of Engineering should make an appointment with John Stratman [Academic Advising Center, 1255 Angell Hall, 734.764.0332] and then make an appointment to see a chemistry department advisor online.

Grade Policies

The department strongly recommends that a student earn a grade of at least C– in all CHEM courses and mathematics, physics, and biology courses which are prerequisites for subsequent elections. A major program grade point average of at least 2.0 is required; this includes chemistry courses, mathematics and physics prerequisites and advanced electives which are part of a plan for the major. Prerequisites must be taken for a grade. Students must request any change in a grade before the end of the next regular academic term.

 

Prerequisites

    • BIOLOGY 171 and either 172 or 174; or BIOLOGY 192; or BIOLOGY 195
    • CHEM 210/211 and CHEM 215
    • MATH 115 (or 120) and MATH 116 (or 121)
    • MATH 215 or CHEM 262
    • PHYSICS [125/127 or 135/136 or 139 or 140/141 or 160/161] and PHYSICS [126/128 or 235/236 or 239 or 240/241 or 260/261].

 

Requirements

Minimum Credits: 37

Must include:

  1. Core: BIOLOGY 305; CHEM 260, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352, 451, 452, 453.
    *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM / BIOPHYS / PHYSICS 417: Dynamic Biophysics (3)
    • CHEM 420: Advanced Organic Chemistry (3)
    • CHEM / BIOPHYS 440: Biophysics of Disease (3)
    • CHEM 447: Physical Methods of Analysis (3)
    • CHEM 454: Biophysical Chem II: Macromolecular Structure, Dynamics (3)
    • CHEM 455: Special Topics in Biochemistry (3)
    • CHEM 461: Physical Chemistry I (3)
    • CHEM / AOSS 467 / EARTH 465 / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • CHEM / BIOPHYS 521: Biophysical Chemistry II (3)
    • CHEM / BIOLCHEM / MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • CHEM / BIOLCHEM 673: Enzyme Kinetics (2)
    • AOSS / CHEM 467 / EARTH 465 / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • BIOLCHEM / CHEM / MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • BIOLCHEM / CHEMBIO 530: Structural Biology (3)
    • BIOLCHEM 541: Molecular Genetics (3)
    • BIOLCHEM 550: Macromolecular Structure and Function (3)
    • BIOLCHEM / PHYSIOL / PHRMACOL 576: Signal transduction (1)
    • BIOLCHEM 640: Post-transcriptional Gene Regulation (2)
    • BIOLCHEM 650: Mechanisms of Eukaryotic Gene Expression (3)
    • BIOLCHEM / CHEM 673: Enzyme Kinetics (2)
    • BIOLCHEM / CDB / MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • BIOPHYS 417/CHEM 417/PHYSICS 417: Dynamical Processes in Biophysics (3)
    • BIOPHYS 420: Structural Biology I (3) (only if taken W17 or later)
    • BIOPHYS / PHYSICS 430: Medical Physics (3) (only if taken WN20 or later)
    • BIOPHYS 435: Biophysical Modeling (3)
    • BIOPHYS / CHEM 440: Biophysics of Disease (3)
    • BIOPHYS / CHEM 521: Biophysical Chemistry II (3)
    • CDB / BIOLCHEM / MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • CHEMBIO / BIOLCHEM 530: Structural Biology (3)
    • EARTH 465 / CHEM / AOSS / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • ENSCEN / CHEM / AOSS 367 / EARTH / ENVIRON 467: Biogeochemical Cycles (3)
    • ENVIRON / CHEM / AOSS 467 /EARTH 465 / ENSCEN 467: Biogeochemical Cycles (3)
    • MCDB 405: Molecular Basis of Development (3)
    • MCDB 411: Protein Biochemistry) (3)
    • MCDB 417: Chromosome Structure and Function (3)
    • MCDB 418: Endocrinology (3)
    • MCDB 422: Brain Development, Plasticity, and Circuits (3) (only if taken W17 or later)
    • MCDB 427: Molecular Biology (3)
    • MCDB 428: Cell Biology (3)
    • MCDB 431: Plant Biochemistry (3)
    • MCDB 435: Intracellular Trafficking (3)
    • MCDB 436: Introductory Immunology (3)
    • MCDB 437: Microbial Communities & Development (3)
    • MCDB 441: Cell Biology of Disease (3)
    • MCDB 471: Advanced Methods in Biochemistry (3)
    • MEDCHEM / BIOLCHEM / CHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • MICRBIOL / BIOLCHEM / CDB 675: Advanced Topics in Protein Trafficking and Localization (2)
    • PHRMACOL 576/BIOLCHEM 576/PHYSIOL 576: Signal transduction (1)
    • PHYSICS / CHEM / BIOPHYS 417: Dynamic Biophysics (3)
    • PHYSICS / BIOPHYS 430: Medical Physics (3) (only if taken WN20 or later)
    • PHYSIOL / BIOLCHEM / PHRMACOL 576: Signal transduction (1)
  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are MCDB 429, CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Honors

Qualified students may elect an Honors major. The Honors major requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

Teaching Certificate

Those seeking a B.S. or B.S. Chem. Degree with a teaching certificate in Chemistry must fulfill departmental as well as School of Education requirements. Students who plan to earn a teaching certificate with a teaching major or minor in Chemistry should contact the School of Education Teacher Education Office.

Biochemistry [B.S.] (Major) (Fall 2018 - Fall 2019)

Effective Fall 2018

Exclusions:

Students who elect a major in Biochemistry may not elect the following majors: Biology; General Biology; Molecular, Cellular, and Developmental Biology (formerly known as Cell and Molecular Biology, or CMB); Cellular and Molecular Biomedical Science Major (formerly known as Cellular and Molecular Biology and Biomedical Engineering, or CMB:BME); Ecology and Evolutionary Biology; Microbiology; or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

Advising

Students develop a plan for the major in consultation with a program advisor. Those interested in a B.S. degree with a major in Chemical Science (120 credits) or the specialized program leading to the Bachelor of Science in Chemistry (124 credits) are urged to consult a program advisor during the freshman and/or sophomore years. Prospective majors are advised that further study in chemistry requires adequate performance in early chemistry courses (preferably B- or better) as well as in the mathematics and physics prerequisites. Students interested in an Honors degree should see the Chemistry Honors advisor. Appointments are scheduled online at http://lsa.umich.edu/chem/undergraduates/advising.html. Students interested in the joint program with the College of Engineering should make an appointment with John Stratman [Academic Advising Center, 1255 Angell Hall, 734.764.0332] and then make an appointment to see a chemistry department advisor online.

Grade Policies

The department strongly recommends that a student earn a grade of at least C– in all CHEM courses and mathematics, physics, and biology courses which are prerequisites for subsequent elections. A major program grade point average of at least 2.0 is required; this includes chemistry courses, mathematics and physics prerequisites and advanced electives which are part of a plan for the major. Prerequisites must be taken for a grade. Students must request any change in a grade before the end of the next regular academic term.

 

Prerequisites

    • BIOLOGY 171 and either 172 or 174; or BIOLOGY 192; or BIOLOGY 195
    • CHEM 210/211 and CHEM 215
    • MATH 115 (or 120) and MATH 116 (or 121)
    • MATH 215 or CHEM 262
    • PHYSICS [125/127 or 135/136 or 139 or 140/141 or 160/161] and PHYSICS [126/128 or 235/236 or 239 or 240/241 or 260/261].

 In cases where a student is transferring to Biochemistry from outside the University or is entering later, from another major, the student may be awarded an override for Genetics after completion of only one of either BIOLOGY 171 or 172 where taking the other would be a burden for timely graduation. The override request must come from a Biochemistry department advisor along with the assurance that the student has been informed of the material from BIOLOGY 171 or 172 that he or she needs to review prior to enrolling in the Genetics course.

Requirements

Minimum Credits: 37

Must include:

  1. Core: BIOLOGY 305; CHEM 260, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352, 451, 452, 453.
    *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM / BIOPHYS / PHYSICS 417: Dynamic Biophysics (3)
    • CHEM 420: Advanced Organic Chemistry (3)
    • CHEM / BIOPHYS 440: Biophysics of Disease (3)
    • CHEM 447: Physical Methods of Analysis (3)
    • CHEM 454: Biophysical Chem II: Macromolecular Structure, Dynamics (3)
    • CHEM 455: Special Topics in Biochemistry (3)
    • CHEM 461: Physical Chemistry I (3)
    • CHEM / AOSS 467 / EARTH 465 / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • CHEM / BIOPHYS 521: Biophysical Chemistry II (3)
    • CHEM / BIOLCHEM / MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • CHEM / BIOLCHEM 673: Enzyme Kinetics (2)
    • AOSS / CHEM 467 / EARTH 465 / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • BIOLCHEM / CHEM / MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • BIOLCHEM / CHEMBIO 530: Structural Biology (3)
    • BIOLCHEM 541: Molecular Genetics (3)
    • BIOLCHEM 550: Macromolecular Structure and Function (3)
    • BIOLCHEM / PHYSIOL / PHRMACOL 576: Signal transduction (1)
    • BIOLCHEM 640: Post-transcriptional Gene Regulation (2)
    • BIOLCHEM 650: Mechanisms of Eukaryotic Gene Expression (3)
    • BIOLCHEM / CHEM 673: Enzyme Kinetics (2)
    • BIOLCHEM / CDB / MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • BIOPHYS / CHEM / PHYSICS 417: Dynamical Processes in Biophysics (3)
    • BIOPHYS 420: Structural Biology I (3) (only if taken W17 or later)
    • BIOPHYS / PHYSICS 430: Medical Physics (3) (only if taken WN20 or later)
    • BIOPHYS 435: Biophysical Modeling (3)
    • BIOPHYS / CHEM 440: Biophysics of Disease (3)
    • BIOPHYS / CHEM 521: Biophysical Chemistry II (3)
    • CDB / BIOLCHEM / MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • CHEMBIO / BIOLCHEM 530: Structural Biology (3)
    • EARTH 465 / CHEM / AOSS / ENSCEN / ENVIRON 467: Biogeochemical Cycles (3)
    • ENSCEN / CHEM / AOSS 467 / EARTH 465 / ENVIRON 467: Biogeochemical Cycles (3)
    • ENVIRON / CHEM / AOSS 467 / EARTH 465 / ENSCEN 467: Biogeochemical Cycles (3)
    • MCDB 405: Molecular Basis of Development (3)
    • MCDB 411: Protein Biochemistry) (3)
    • MCDB 417: Chromosome Structure and Function (3)
    • MCDB 418: Endocrinology (3)
    • MCDB 422: Brain Development, Plasticity, and Circuits (3) (only if taken W17 or later)
    • MCDB 427: Molecular Biology (3)
    • MCDB 428: Cell Biology (3)
    • MCDB 431: Plant Biochemistry (3)
    • MCDB 435: Intracellular Trafficking (3)
    • MCDB 436: Introductory Immunology (3)
    • MCDB 437: Microbial Communities & Development (3)
    • MCDB 441: Cell Biology of Disease (3)
    • MCDB 471: Advanced Methods in Biochemistry (3)
    • MEDCHEM / BIOLCHEM / CHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • MICRBIOL / BIOLCHEM / CDB 675: Advanced Topics in Protein Trafficking and Localization (2)
    • PHRMACOL / BIOLCHEM / PHYSIOL 576: Signal transduction (1)
    • PHYSICS / CHEM / BIOPHYS 417: Dynamic Biophysics (3)
    • PHYSIOL / BIOLCHEM / PHRMACOL 576: Signal transduction (1)
  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are MCDB 429, CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Distribution Policy

No course used to fulfill a major requirement may be used toward the LSA Distribution Requirement. In addition, courses in the CHEM and BIOLCHEM

Honors

Qualified students may elect an Honors major. The Honors major requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

Teaching Certificate

Those seeking a B.S. or B.S. Chem. Degree with a teaching certificate in Chemistry must fulfill departmental as well as School of Education requirements. Students who plan to earn a teaching certificate with a teaching major or minor in Chemistry should contact the School of Education Teacher Education Office.

Biochemistry [B.S.] (Major) (Fall 2015 - Summer 2018)

Effective Fall 2015

Exclusions:

Students who elect a major in Biochemistry may not elect the following majors: Biology, General Biology, Cell and Molecular Biology, CMB:Biomedical Engineering, Ecology and Evolutionary Biology, Microbiology, or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

Advising

Students develop a plan for the major in consultation with a program advisor. Those interested in a B.S. degree with a major in Chemical Science (120 credits) or the specialized program leading to the Bachelor of Science in Chemistry (124 credits) are urged to consult a program advisor during the freshman and/or sophomore years. Prospective majors are advised that further study in chemistry requires adequate performance in early chemistry courses (preferably B- or better) as well as in the mathematics and physics prerequisites. Students interested in an Honors degree should see the Chemistry Honors advisor. Appointments are scheduled online at http://lsa.umich.edu/chem/undergraduates/advising.html. Students interested in the joint program with the College of Engineering should make an appointment with John Stratman [Academic Advising Center, 1255 Angell Hall, 734.764.0332] and then make an appointment to see a chemistry department advisor online.

Grade Policies

The department strongly recommends that a student earn a grade of at least C– in all CHEM courses and mathematics, physics, and biology courses which are prerequisites for subsequent elections. A major program grade point average of at least 2.0 is required; this includes chemistry courses, mathematics and physics prerequisites and advanced electives which are part of a plan for the major. Prerequisites must be taken for a grade. Students must request any change in a grade before the end of the next regular academic term.

 

Prerequisites

    • BIOLOGY 171 and 172
    • CHEM 210/211, 215
    • MATH 115 (or 120), 116 (or 121), 215 (or the equivalent)
    • PHYSICS [135/136 or 140/141] and [235/236 or 240/241].

 In cases where a student is transferring to Biochemistry from outside the University or is entering later, from another major, the student may be awarded an override for Genetics after completion of only one of either BIOLOGY 171 or 172 where taking the other would be a burden for timely graduation. The override request must come from a Biochemistry department advisor along with the assurance that the student has been informed of the material from BIOLOGY 171 or 172 that he or she needs to review prior to enrolling in the Genetics course.

Requirements

Must include:

  1. Core: BIOLOGY 305; CHEM 260, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352, 451, 452, 453.
    *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM 417/BIOPHYS 417/PHYSICS 417: Dynamic Biophysics (3)
    • CHEM 420: Advanced Organic Chemistry (3)
    • CHEM 440/BIOPHYS 440: Biophysics of Disease (3)
    • CHEM 447: Physical Methods of Analysis (3)
    • CHEM 454: Biophysical Chem II: Macromolecular Structure, Dynamics (3)
    • CHEM 455: Special Topics in Biochemistry (3)
    • CHEM 461: Physical Chemistry I (3)
    • CHEM 467/AOSS 467/EARTH 465/ENSCEN 467/ENVIRON 467: Biogeochemical Cycles (3)
    • CHEM 521/BIOPHYS 521: Biophysical Chemistry II (3)
    • CHEM 528/BIOLCHEM 528/MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • CHEM 673/BIOLCHEM 673: Enzyme Kinetics (2)
    • AOSS 467/CHEM 467/EARTH 465/ENSCEN 467/ENVIRON 467: Biogeochemical Cycles (3)
    • BIOLCHEM 528/CHEM 528/MEDCHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • BIOLCHEM 530/CHEMBIO 530: Structural Biology (3)
    • BIOLCHEM 541: Molecular Genetics (3)
    • BIOLCHEM 550: Macromolecular Structure and Function (3)
    • BIOLCHEM 576/PHYSIOL 576/PHRMACOL 576: Signal transduction (1)
    • BIOLCHEM 640: Post-transcriptional Gene Regulation (2)
    • BIOLCHEM 650: Mechanisms of Eukaryotic Gene Expression (3)
    • BIOLCHEM 673/CHEM 673: Enzyme Kinetics (2)
    • BIOLCHEM 675/CDB 675/MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • BIOPHYS 417/CHEM 417/PHYSICS 417: Dynamical Processes in Biophysics (3)
    • BIOPHYS 420: Structural Biology I (3) (W17)
    • BIOPHYS 435: Biophysical Modeling (3)
    • BIOPHYS 440/CHEM 440: Biophysics of Disease (3)
    • BIOPHYS 521/CHEM 521: Biophysical Chemistry II (3)
    • CDB 675/BIOLCHEM 675/MICRBIOL 675: Advanced Topics in Protein Trafficking and Localization (2)
    • CHEMBIO 530/BIOLCHEM 530: Structural Biology (3)
    • EARTH 465/CHEM 467/AOSS 467/ ENSCEN 467/ENVIRON 467: Biogeochemical Cycles (3)
    • ENSCEN 467/CHEM 467/AOSS 467/EARTH 465/ENVIRON 467: Biogeochemical Cycles (3)
    • ENVIRON 467/CHEM 467/AOSS 467/EARTH 465/ENSCEN 467: Biogeochemical Cycles (3)
    • MCDB 405: Molecular Basis of Development (3)
    • MCDB 411: Protein Biochemistry) (3)
    • MCDB 417: Chromosome Structure and Function (3)
    • MCDB 418: Endocrinology (3)
    • MCDB 422: Brain Development, Plasticity, and Circuits (3) (W17)
    • MCDB 427: Molecular Biology (3)
    • MCDB 428: Cell Biology (3)
    • MCDB 431: Plant Biochemistry (3)
    • MCDB 435: Intracellular Trafficking (3)
    • MCDB 436: Introductory Immunology (3)
    • MCDB 437: Microbial Communities & Development (3)
    • MCDB 441: Cell Biology of Disease (3)
    • MCDB 471: Advanced Methods in Biochemistry (3)
    • MEDCHEM 528/BIOLCHEM 528/CHEM 528: Enzyme Mechanisms, Ligand Binding (2)
    • MICRBIOL 675/BIOLCHEM 675/CDB 675: Advanced Topics in Protein Trafficking and Localization (2)
    • PHRMACOL 576/BIOLCHEM 576/PHYSIOL 576: Signal transduction (1)
    • PHYSICS 417CHEM 417/BIOPHYS 417: Dynamic Biophysics (3)
    • PHYSIOL 576/BIOLCHEM 576/PHRMACOL 576: Signal transduction (1)
  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are MCDB 429, CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Distribution Policy

No course used to fulfill a major requirement may be used toward the LSA Distribution Requirement. In addition, courses in the CHEM and BIOLCHEM

Honors

Qualified students may elect an Honors major. The Honors major requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

Teaching Certificate

Those seeking a B.S. or B.S. Chem. Degree with a teaching certificate in Chemistry must fulfill departmental as well as School of Education requirements. Students who plan to earn a teaching certificate with a teaching major or minor in Chemistry should contact the School of Education Teacher Education Office.

Biochemistry Major (B.S.) (Fall 2012-Summer 2015)

May be elected as an interdepartmental major

Effective Date: Fall 2012-Summer 2015

Exclusions: Students who elect a major in Biochemistry may not elect the following majors: Biology, General Biology; Cell and Molecular Biology; CMB:Biomedical Engineering; Ecology and Evolutionary Biology; Microbiology; or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

The biochemistry major is intended for students interested in the chemical basis of biological phenomena. This degree program is ideal for students who are interested in learning about life from a chemical perspective. The major is intellectually demanding and is intended to prepare students for further education (graduate school or medicine). Students will gain a solid foundation in chemistry through traditional sub-discipline courses, but will also take a number of chemistry courses that are focused on the role of chemistry in biological systems. Students will also have the option to take elective courses in molecular biology, and also may pursue undergraduate research in lieu of one of the traditional laboratory courses. A B.S. degree in biochemistry is also a useful means of preparing for jobs in academic medical centers, the pharmaceutical industry, and in biotechnology companies. Students that pursue this degree will be well equipped for graduate studies in biochemistry, chemical biology, and many other fields of inquiry in the life sciences. The degree will also provide excellent preparation for students intending to pursue professional careers in the Biotechnology Industry as well as the Health Sciences. Because the major is highly structured, it is essential that prospective majors follow the guidelines set forth below.

Prerequisites to the Major

  • BIOLOGY 171 and 172
  • CHEM 210/211, 215
  • MATH 115, 116, 215 (or the equivalent)
  • PHYSICS [135 or 140]/141 and [235 or 240]/241.

In cases where a student is transferring to Biochemistry from outside the University or is entering later, from another major, the student may be awarded an override for Genetics after completion of only one of either BIOLOGY 171 or 172, and where taking the other would be a burden for timely graduation. The override request must come from a Biochemistry department advisor along with the assurance that the student has been informed of the material from BIOLOGY 171 or 172 that he or she needs to review prior to enrolling in the Genetics course.

Program of study in a major

Must include:

  1. Core: BIOLOGY 305; CHEM 260, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352, 451, 452, 453.
         *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM 417/BIOPHYS 417/PHYSICS 417 (3) Dynamic Biophysics
    • CHEM 420 (3) Advanced Organic Chemistry
    • CHEM 440/BIOPHYS 440 (3) Biophysics of Disease
    • CHEM 447 (3) Physical Methods of Analysis
    • CHEM 454 (3) Biophysical Chem II: Macromolecular Structure, Dynamics
    • CHEM 455 (3) Special Topics in Biochemistry
    • CHEM 461 (3) Physical Chemistry I
    • CHEM 467/AOSS 467/EARTH 465/ENSCEN 467/ENVIRON 467 (3) Biogeochemical Cycles
    • CHEM 521/BIOPHYS 521 (3) Biophysical Chemistry II
    • CHEM 528/BIOLCHEM 528/MEDCHEM 528 (2) Enzyme Mechanisms, Ligand Binding,
    • CHEM 673/BIOLCHEM 673 (2) Enzyme Kinetics
    • AOSS 467/CHEM 467/EARTH 465/ENSCEN 467/ENVIRON 467 (3) Biogeochemical Cycles
    • BIOLCHEM 528/CHEM 528/MEDCHEM 528 (2) Enzyme Mechanisms, Ligand Binding,
    • BIOLCHEM 530/CHEMBIO 530 (3) Structural Biology
    • BIOLCHEM 541 (3) Molecular Genetics
    • BIOLCHEM 550 (3) Macromolecular Structure and Function
    • BIOLCHEM 576/PHYSIOL 576/PHRMACOL 576 (1) Signal transduction
    • BIOLCHEM 640 (2) Post-transcriptional Gene Regulation
    • BIOLCHEM 650 (3) Mechanisms of Eukaryotic Gene Expression
    • BIOLCHEM 673/CHEM 673 (2) Enzyme Kinetics
    • BIOLCHEM 675/CDB 675/MICRBIOL 675 (2) Advanced Topics in Protein Trafficking and Localization
    • BIOPHYS 417/CHEM 417/PHYSICS 417 (3) Dynamical Processes in Biophysics
    • BIOPHYS 435 (3) Biophysical Modeling
    • BIOPHYS 440/CHEM 440 (3) Biophysics of Disease
    • BIOPHYS 521/CHEM 521 (3) Biophysical Chemistry II
    • CDB 675/BIOLCHEM 675/MICRBIOL 675 (2) Advanced Topics in Protein Trafficking and Localization
    • CHEMBIO 530/BIOLCHEM 530 (3) Structural Biology
    • EARTH 465/CHEM 467/AOSS 467/ ENSCEN 467/ENVIRON 467 (3) Biogeochemical Cycles
    • ENSCEN 467/CHEM 467/AOSS 467/EARTH 465/ENVIRON 467 (3) Biogeochemical Cycles
    • ENVIRON 467/CHEM 467/AOSS 467/EARTH 465/ENSCEN 467 (3) Biogeochemical Cycles
    • MCDB 405 (3) Molecular Basis of Development
    • MCDB 411 (3) Protein Biochemistry)
    • MCDB 417 (3) Chromosome Structure and Function
    • MCDB 418 (3) Endocrinology
    • MCDB 427 (3) Molecular Biology
    • MCDB 428 (3) Cell Biology
    • MCDB 431 (3) Plant Biochemistry
    • MCDB 435 (3) Intracellular Trafficking
    • MCDB 436 (3) Introductory Immunology
    • MCDB 437 (3) Microbial Communities & Development
    • MCDB 441 (3) Cell Biology of Disease
    • MCDB 471 - Advanced Methods in Biochemistry
    • MEDCHEM 528/BIOLCHEM 528/CHEM 528 (2) Enzyme Mechanisms, Ligand Binding,
    • MICRBIOL 675/BIOLCHEM 675/CDB 675 (2) Advanced Topics in Protein Trafficking and Localization
    • PHRMACOL 576/BIOLCHEM 576/PHYSIOL 576 (1) Signal transduction
    • PHYSICS 417CHEM 417/BIOPHYS 417 (3) Dynamic Biophysics
    • PHYSIOL 576/BIOLCHEM 576/PHRMACOL 576 (1) Signal transduction
  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are MCDB 429,  CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Honors Plan

Qualified students may elect an Honors Plan. This program requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

Biochemistry Major (B.S.) (Fall 2012-Fall 2013)

May be elected as an interdepartmental major

Effective Fall 2012 through Fall 2013

Exclusions: Students who elect a major in Biochemistry may not elect the following majors: Biology, General Biology; Cell and Molecular Biology; CMB:Biomedical Engineering; Ecology and Evolutionary Biology; Microbiology; or Neuroscience. They may also not elect a minor in Biology, or any of the Chemistry minors.

The biochemistry major is intended for students interested in the chemical basis of biological phenomena. This degree program is ideal for students who are interested in learning about life from a chemical perspective. The major is intellectually demanding and is intended to prepare students for further education (graduate school or medicine). Students will gain a solid foundation in chemistry through traditional sub-discipline courses, but will also take a number of chemistry courses that are focused on the role of chemistry in biological systems. Students will also have the option to take elective courses in molecular biology, and also may pursue undergraduate research in lieu of one of the traditional laboratory courses. A B.S. degree in biochemistry is also a useful means of preparing for jobs in academic medical centers, the pharmaceutical industry, and in biotechnology companies.Students that pursue this degree will be well equipped for graduate studies in biochemistry, chemical biology, and many other fields of inquiry in the life sciences. The degree will also provide excellent preparation for students intending to pursue professional careers in the Biotechnology Industry as well as the Health Sciences. Because the major is highly structured, it is essential that prospective majors follow the guidelines set forth below.

Prerequisites to the Major

  • BIOLOGY 171 and 172
  • CHEM 210/211, 215
  • MATH 115, 116, 215 (or the equivalent)
  • PHYSICS [135 or 140]/141 and [235 or 240]/241.

In cases where a student is transferring to Biochemistry from outside the University or is entering later, from another major, the student may be awarded an override for Genetics after completion of only one of either BIOLOGY 171 or 172, and where taking the other would be a burden for timely graduation. The override request must come from a Biochemistry department advisor along with the assurance that the student has been informed of the material from BIOLOGY 171 or 172 that he or she needs to review prior to enrolling in the Genetics course.

Program of study in a major

Must include:

  1. Core: BIOLOGY 305; CHEM 260, [302 or 303 or 241 or 245], [216 or 242 (or 246 and 247)] 351*, 352, 451, 452, 453.
         *Students are strongly encouraged to take CHEM 351 but could substitute this course requirement with MCDB 310 or BIOLCHEM 415.
  2. Electives: A total of at least six credits chosen from:
    • CHEM 417/BIOPHYS 417/PHYSICS 417 (3) Dynamic Biophysics
    • CHEM 420 (3) Advanced Organic Chemistry
    • CHEM 440/BIOPHYS 440 (3) Biophysics of Disease
    • CHEM 447 (3) Physical Methods of Analysis
    • CHEM 454 (3) Biophysical Chem II: Macromolecular Structure, Dynamics
    • CHEM 461 (3) Physical Chemistry I
    • CHEM 467/AOSS 467/EARTH 465/ENSCEN 467/ENVIRON 467 (3) Biogeochemical Cycles
    • CHEM 521/BIOPHYS 521 (3) Biophysical Chemistry II
    • CHEM 528/BIOLCHEM 528/MEDCHEM 528 (2) Enzyme Mechanisms, Ligand Binding,
    • CHEM 673/BIOLCHEM 673 (2) Enzyme Kinetics
    • AOSS 467/CHEM 467/EARTH 465/ENSCEN 467/ENVIRON 467 (3) Biogeochemical Cycles
    • BIOLCHEM 528/CHEM 528/MEDCHEM 528 (2) Enzyme Mechanisms, Ligand Binding,
    • BIOLCHEM 530/CHEMBIO 530 (3) Structural Biology
    • BIOLCHEM 541 (3) Molecular Genetics
    • BIOLCHEM 550 (3) Macromolecular Structure and Function
    • BIOLCHEM 576/PHYSIOL 576/PHRMACOL 576 (1) Signal transduction
    • BIOLCHEM 640 (2) Post-transcriptional Gene Regulation
    • BIOLCHEM 650 (3) Mechanisms of Eukaryotic Gene Expression
    • BIOLCHEM 673/CHEM 673 (2) Enzyme Kinetics
    • BIOLCHEM 675/CDB 675/MICRBIOL 675 (2) Advanced Topics in Protein Trafficking and Localization
    • BIOPHYS 417/CHEM 417/PHYSICS 417 (3) Dynamical Processes in Biophysics
    • BIOPHYS 435 (3) Biophysical Modeling
    • BIOPHYS 440/CHEM 440 (3) Biophysics of Disease
    • BIOPHYS 521/CHEM 521 (3) Biophysical Chemistry II
    • CDB 675/BIOLCHEM 675/MICRBIOL 675 (2) Advanced Topics in Protein Trafficking and Localization
    • CHEMBIO 530/BIOLCHEM 530 (3) Structural Biology
    • EARTH 465/CHEM 467/AOSS 467/ ENSCEN 467/ENVIRON 467 (3) Biogeochemical Cycles
    • ENSCEN 467/CHEM 467/AOSS 467/EARTH 465/ENVIRON 467 (3) Biogeochemical Cycles
    • ENVIRON 467/CHEM 467/AOSS 467/EARTH 465/ENSCEN 467 (3) Biogeochemical Cycles
    • MCDB 405 (3) Molecular Basis of Development
    • MCDB 411 (3) Protein Biochemistry)
    • MCDB 417 (3) Chromosome Structure and Function
    • MCDB 418 (3) Endocrinology
    • MCDB 427 (3) Molecular Biology
    • MCDB 428 (3) Cell Biology
    • MCDB 431 (3) Plant Biochemistry
    • MCDB 435 (3) Intracellular Trafficking
    • MCDB 436 (3) Introductory Immunology
    • MCDB 437 (3) Microbial Communities & Development
    • MCDB 441 (3) Cell Biology of Disease
    • MCDB 471 - Advanced Methods in Biochemistry
    • MEDCHEM 528/BIOLCHEM 528/CHEM 528 (2) Enzyme Mechanisms, Ligand Binding,
    • MICRBIOL 675/BIOLCHEM 675/CDB 675 (2) Advanced Topics in Protein Trafficking and Localization
    • PHRMACOL 576/BIOLCHEM 576/PHYSIOL 576 (1) Signal transduction
    • PHYSICS 417CHEM 417/BIOPHYS 417 (3) Dynamic Biophysics
    • PHYSIOL 576/BIOLCHEM 576/PHRMACOL 576 (1) Signal transduction
  3. An advanced laboratory or undergraduate research course. Recommended options for the advanced laboratory course are MCDB 429,  CHEM 482 or 483; or four credits of undergraduate research elected as any combination of either CHEM 398 or BIOLCHEM 398, by permission of the department advisor. Students electing the undergraduate research option must execute an extended research project under the supervision of a faculty member who agrees to oversee the project.

Honors Plan

Qualified students may elect an Honors major. This program requires a thesis which describes and analyzes independent experimental work. The research topic and advisor must be approved by the Honors advisor in Biochemistry. Students in this program are expected to maintain an overall grade point average above 3.4 and at least a 3.4 in the field of the major, including prerequisite courses. CHEM 398 (4 credits) and the thesis course, CHEM 498, replaces the requirement for an upper-level laboratory course outlined above.

 

Teaching Certificate

Those seeking a B.S. or B.S. CHEM. degree with a teaching certificate in Chemistry must fulfill departmental as well as School of Education requirements. Students who plan to earn a teaching certificate with a teaching major or minor in Chemistry should contact the School of Education Office of Academic Services.