Fundamental questions remain unanswered in understanding galactic-scale star formation, despite many decades of investigation and progress. These include: how do stars cluster in galaxies, and how do these structures evolve in time? Do we actually have "clustered" and "diffused" modes of star formation? When structures remain bound (star clusters), how do their populations evolve? How are they related to the galactic-scale star formation? Is the stellar Initial Mass Function universal? How are popular star formation rate indicators affected by the recent star formation history of a galaxy? How are these effects impacting our understanding of the scaling laws of star formation with the gas reservoir? The answers to these questions inform our theories for the evolution of galaxies through cosmic times. Many of these questions are being addressed by recent projects that combine UV and high-angular resolution with the Hubble Space Telescope, and which I will describe together with the results they have obtained so far.