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MCDB Shared Imaging Labs

Please note that you may be required to obtain permission or training from the equipment caretaker before use.

The MCDB department provides several research-grade microscopes with image capture systems to assist researchers with their sample imaging. These microscopes include:

  • Leica SP5 laser scanning confocal microscope with 405, 458, 476, 488, 514, 561, and 633nm laser excitation lines available, spectral detection, superfast resonant scanner, and many other features.
  • FEI/Philips CM100 Biotwin transmission electron microscope (EM) with a Kodak 4.2i, bottom-mount digital camera.
  • Zeiss LSM510 laser scanning confocal microscope with 458, 488, 514, and 543nm laser excitation lines available.
  • Nikon E600 fluorescence microscope with a SPOT RT Slider camera, and 4x, 10x, 20x, 40x, and 100x oil objective lenses. The SPOT camera is a grayscale detector, for fluorescence sensitivity, with a three color filter wheel to obtain detailed color images.
  • Olympus IX81 inverted fluorescence microscope with motorized Z movement, a Retiga 1300R Fast, cooled, monochrome camera and 4x, 10x, 20x, and 40x objective lenses.
  • Leica MZ FLIII fluorescence stereomicroscope with a Leica DC480, 5MP color camera and microscope dichroics for green fluorescence detection.
  • Andor/Olympus spinning disk confocal microscope imaging system with 405, 458, 488, 514, 561, and 640nm laser excitation lines, 10x, 20x, 60x, and 100x objective lenses, a FRAP module, continuous focus feature, streaming mode, Photometrics dual view DV2 module, live cell incubation chamber, lens heater, and an Andor iXon Ultra CCD camera. 

The MCDB Imaging Labs contain advanced microscope equipment, image capture systems, software, and other resources available to all MCDB researchers and collaborators. This shared equipment is provided by the department to best aid as many research labs as possible.

Please speak with Gregg Sobocinski ( or 734.615.2034) before using any of these microscopes. If you have any questions about microscope technologies or accessories available within the MCDB department, please feel free to speak with Gregg. He will be happy to assist you with using these microscopes to their optimal capabilities, or will recommend other University of Michigan resources, as appropriate.

Reserve Equipment

To reserve the confocal or EM please use the Confocal and EM Sign-up Calendar. (on sharepoint)
A UMROOT password is required.