Have you ever wondered how life experiences are translated into changes in the DNA and how these in turn affect behavior? Most of us know that a genome is the blueprint used to build and maintain an organism. While genomes are in fact hidden inside cells, they are also influenced by the “experience” of cells and organisms. These experiences, which come in the many forms, from diet to pollutants to stress, alter the chemical nature of the genome, and in turn, its function. This is particularly crucial in the brain, as its function is linked to behavior.

This class will cross the lines between neuroscience, molecular biology and epigenetics to uncover the effect of the environment and life experience on brain function and behavior. We will first examine how genes determine complex behaviors, and then analyze in depth how ancestral dietary stress, maternal behavior, social stress, and more, affect gene expression to contribute to brain function and dysfunction.

Course Requirements:

This course involves critical reading and class discussion of recently published research articles in the field of neuroepigenetics.

Assessments will include class interactions, quizzes and a final project where students will be asked to write an essay for the public and record a podcast on a topic related to those covered in class. Google "Neuroepic" for more information.