This lecture/discussion course covers evolutionary biology through examination of its conceptual framework and current research topics. We will consider 30 basic concepts of evolutionary biology, including: phase space and fitness landscape; indirect and direct evidence for past evolution; methods of phylogenetic reconstructions; history of the Earth and life; generalizations emerging from past evolution; cases of direct observations of evolution in nature in the course of domestication and in the context of medicine; the basics of population biology, including coalescence and density regulation; Mendelian and multifactorial variation within populations; factors of microevolution, including mutation, selection, mode of reproduction, population structure, and random drift; the basics of theory of microevolution, including the theory of positive, negative, and weak selection and inverse problems; data on evolution of natural populations; species and speciation; and macroevolution of genomes, complex phenotypes, populations and ecosystems.
Course Requirements:
Six components, each worth 1/6 of the total 1) a quiz after each lecture that consists of one question. Students are encouraged to discuss this question with peers, but are expected to write answers independently. Three worst grades will be ignored. 2) Active participation in discussions. 3) Midterm I, covering the material of lectures 1-11. 4) Midterm II, covering the material of lectures 12-24. 5) A term paper, written in Nature "News and Views" style, that deals with a subject from current literature, chosen by the student in coordination with the instructor. 6) Comprehensive final exam.
Intended Audience:
Biology majors, mostly juniors, who are interested in evolutionary biology and are ready for a quantitative treatment of its basic concepts and results. EEB 391 covers material similar to that of EEB 390. The purpose of EEB 391 is to provide a more formal and quantitative treatment of the basics of evolutionary biology, suitable for a student who has some command of mathematics and is willing to apply it to a biological subject.
Class Format:
3 hours of lectures and 1.5 hours of discussions