If dark matter carries baryon and/or lepton number, a DM particle may annihilate with a nucleon by flipping to anti-DM. We introduce a model where DM is asymmetric and carries B and L as -1/2. It can annihilate with a nucleon to meson, lepton and anti-DM. Such signal may be observed in proton decay experiments, similar signal has been studied in detail in arXiv:1008.2399, though in a different channel. If DM is captured in the Sun, the DM induced nucleon decay could generate a large flux of neutrinos, which could be observed in neutrino experiments. Furthermore, the anti-DM particle in the final state obtains a relatively large momentum (few hundred MeV), and escape the Sun. These fast anti-DM particles could also induce interesting signals in various ground experiments.