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*CANCELED*: Thursday Seminar: Sex chromosomes, speciation, and gene regulation in <i>Drosophila</i>

Thursday, November 12, 2015
12:00 AM
1210 Chemistry

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**CANCELED: RESCHEDULE TO BE ANNOUNCED**


Abstract
Sex chromosomes play a special role in the evolution of postzygotic reproductive isolation across a wide range of animal taxa. For reasons that remain unclear, the X chromosome accumulates genetic factors that cause sterility in heterogametic (XY) species hybrids much faster than the autosomes. To determine the evolutionary and genetic basis of this so-called “large X-effect” of speciation, my lab studies three closely related species of the Drosophila simulans complex. I will present evidence from whole-genome analyses that the large X-effect has impacted the history of speciation between these three species. Then, I will present early findings from a massive ultrahigh-resolution genetic mapping analysis. Finally, I will present surprising new discoveries on the unusual transcriptional regulation of X-linked genes in the Drosophila male germline.

Host: Professor Patricia Wittkopp

Coffee and snacks will be served at 4 p.m.

Speaker: